Effect of gold nanoparticle on renal cell: an implication for exposure risk

Ren Fail. 2008;30(3):323-5. doi: 10.1080/08860220701860914.

Abstract

Objective: The objective of this study was to evaluate the effect of gold nanoparticles on renal cell.

Intervention: This study was performed as an experimental study. A mixture of gold nanoparticle solution and renal cell sediment was prepared and further analyzed.

Results: This work revealed that after mixing the renal cell sediment with gold nanoparticle solution, gold nanoparticles can be seen within the renal cells.

Conclusions: Conclusively, the gold nanoparticle can penetrate into renal cell. This is the first report on this observation, and further implies the possibility of other nanoparticle nephrotoxicity in the present nanomaterial era.

MeSH terms

  • Gold / adverse effects*
  • Humans
  • Kidney / cytology*
  • Metal Nanoparticles / adverse effects*
  • Risk Factors

Substances

  • Gold