Evaluation the Clinitek status automated dipstick analysis device for semiquantitative testing of canine urine

Res Vet Sci. 2008 Dec;85(3):467-72. doi: 10.1016/j.rvsc.2008.02.003. Epub 2008 Mar 17.

Abstract

The aim of this prospective study was to evaluate the Clinitek status analyser using Multistix10SG/Microalbustix dipsticks (all: Siemens Dx) for canine urine (n=101) compared to reference methods: visual reading (Combur9 dipstick, Roche), refractometry, microscopy, and quantitative protein/creatinine analysis (Pentra400, AxonLab). The automated analyses were done twice and visual tests were performed by two examiners. An excellent to good concordance was demonstrated between the first/second analysis with the Multistix10SG and the Combur9 dipstick, respectively with Cohen's kappa-values ranging from 0.776 to 1.000. Agreement between both dipsticks was good for glucose (kappa=0.753), blood (kappa=0.793), protein (kappa=0.788), and moderate for bilirubin (kappa=0.431) and ketones (kappa=0.540). In 6/101 specimens, false positive ketone reactions were obtained with the Multistix10SG. Multistix10SG could not be used for determination of pyuria or specific gravity. Semiquantitative/quantitative protein results correlated well (rho=0.90) and creatinine measurements moderately (rho=0.76). Due to automated data transmission to the laboratory information system, the Clinitek status is of advantage in veterinary laboratories/clinics.

MeSH terms

  • Animals
  • Automation
  • Dog Diseases / diagnosis
  • Dog Diseases / urine
  • Dogs / urine*
  • Glycosuria / diagnosis
  • Glycosuria / veterinary
  • Hematuria / diagnosis
  • Hematuria / veterinary
  • Reagent Strips
  • Sensitivity and Specificity
  • Urinalysis / instrumentation
  • Urinalysis / methods
  • Urinalysis / veterinary*

Substances

  • Reagent Strips