Abstract
The appearance and disappearance of polymorphs is no longer a mysterious and inexplicable process. Although methods for polymorph control are still imperfect, there is a large armoury of methods that can be used to tackle this important and challenging problem. We survey the methods and their successes over the last few years.
Publication types
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Research Support, Non-U.S. Gov't
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Review
MeSH terms
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Crystallization / methods*
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Crystallization / trends*
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Humans
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Molecular Structure
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Pharmaceutical Preparations / chemistry*
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Solvents / chemistry
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Technology, Pharmaceutical / methods
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Technology, Pharmaceutical / trends
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Thermodynamics
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X-Ray Diffraction
Substances
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Pharmaceutical Preparations
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Solvents