[Acitretin-induced pneumonia: an underestimated complication of treatment of psoriasis]

Rev Med Interne. 2008 May;29(5):393-6. doi: 10.1016/j.revmed.2007.10.410. Epub 2007 Nov 20.
[Article in French]

Abstract

Introduction: Retinoids are known to induce side effects which can be severe. Alveolar and interstitial pneumonia of uncertain pathogenesis can rarely occur when retinoid are used among patients with psoriasis.

Exegesis: We report an observation of acute respiratory distress beginning 26 days after introduction of acitretin, a second-generation retinoid. Treatment withdrawal and corticotherapy allow a spectacular amelioration of respiratory conditions.

Conclusion: Pneumonia induced by retinoid must be known as a side effect of treatment of psoriasis.

Publication types

  • Case Reports

MeSH terms

  • Acitretin / adverse effects*
  • Adrenal Cortex Hormones / therapeutic use
  • Aged, 80 and over
  • Female
  • Humans
  • Keratolytic Agents / adverse effects*
  • Pneumonia / chemically induced*
  • Pneumonia / diagnostic imaging
  • Pneumonia / drug therapy
  • Psoriasis / drug therapy*
  • Radiography, Thoracic

Substances

  • Adrenal Cortex Hormones
  • Keratolytic Agents
  • Acitretin