Recurrent Trichosporon asahii glossitis: a case report

J Contemp Dent Pract. 2008 Mar 1;9(3):114-20.

Abstract

Aim: This case report aims at describing an infection of the tongue as a manifestation of a Trichosporon asahii infection, its association with bronchial asthma and steroid administration, and to present a review of the literature pertaining to its antifungal susceptibility profile.

Background: Trichosporon asahii has been reported to be associated with a wide spectrum of clinical manifestations, ranging from superficial infection to severe disseminated diseases, particularly in immunocompromised patients.

Case report: A 36-year-old male asthmatic patient with recurrent glossitis presented with a chief complaint of burning sensation and two red areas on the dorsum of the tongue of three months duration. The glossitis was associated with Trichosporon asahii, which had a reduced susceptibility to some azole antifungal agents.

Summary: Trichosporon asahii is an emerging fungal pathogen which may cause a wide range of clinical manifestations. More reports on its various clinical presentations in the oral environment need to be made available in the literature. To date there is a paucity of data on its prevalence, pathogenesis, and antifungal resistance mechanism.

Publication types

  • Case Reports

MeSH terms

  • Administration, Inhalation
  • Adult
  • Antifungal Agents / therapeutic use
  • Asthma / drug therapy
  • Bronchodilator Agents / administration & dosage
  • Bronchodilator Agents / adverse effects
  • Budesonide / administration & dosage
  • Budesonide / adverse effects
  • Drug Resistance, Fungal
  • Glossitis / drug therapy
  • Glossitis / microbiology*
  • Humans
  • Immunocompromised Host
  • Male
  • Mycoses / drug therapy
  • Mycoses / microbiology*
  • Pyrimidines / administration & dosage
  • Pyrimidines / therapeutic use
  • Recurrence
  • Triazoles / administration & dosage
  • Triazoles / therapeutic use
  • Trichosporon*
  • Voriconazole

Substances

  • Antifungal Agents
  • Bronchodilator Agents
  • Pyrimidines
  • Triazoles
  • Budesonide
  • Voriconazole