Saliva composition and functions: a comprehensive review

J Contemp Dent Pract. 2008 Mar 1;9(3):72-80.

Abstract

Aim: The aim of this study was to perform a literature review about the composition and functions of saliva as well as describe the factors that influence salivary flow (SF) and its biochemical composition.

Background: Saliva represents an increasingly useful auxiliary means of diagnosis. Sialometry and sialochemistry are used to diagnose systemic illnesses, monitoring general health, and as an indicator of risk for diseases creating a close relation between oral and systemic health.

Review: This review provides fundamental information about the salivary system in terms of normal values for SF and composition and a comprehensive review of the factors that affect this important system.

Conclusion: Since several factors can influence salivary secretion and composition, a strictly standardized collection must be made so the above-mentioned exams are able to reflect the real functioning of the salivary glands and serve as efficient means for monitoring health.

Clinical significance: Since many oral and systemic conditions manifest themselves as changes in the flow and composition of saliva the dental practitioner is advised to remain up-to-date with the current literature on the subject.

Publication types

  • Review

MeSH terms

  • Age Factors
  • Animals
  • Buffers
  • Humans
  • Saliva / chemistry*
  • Saliva / metabolism
  • Saliva / physiology*
  • Salivary Glands / metabolism
  • Salivary Proteins and Peptides / physiology
  • Secretory Rate
  • Sex Factors
  • Tooth Remineralization

Substances

  • Buffers
  • Salivary Proteins and Peptides