Abstract
This article reviews current understanding of the pathophysiology of fibrosis in systemic sclerosis. It highlights recent discoveries, insights, and emerging research, and potential opportunities for the development of targeted antifibrotic therapies.
MeSH terms
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Animals
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Collagen / metabolism*
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Disease Models, Animal
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Fibroblasts / physiology
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Fibrosis / etiology
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Fibrosis / pathology
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Fibrosis / physiopathology
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Humans
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Mice
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Pericytes / physiology
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Scleroderma, Systemic / diagnosis
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Scleroderma, Systemic / physiopathology*