Vitamin D insufficiency in southern Arizona

Am J Clin Nutr. 2008 Mar;87(3):608-13. doi: 10.1093/ajcn/87.3.608.

Abstract

Background: Vitamin D deficiency or insufficiency has been observed among populations in the northern United States. However, data on the prevalence of vitamin D deficiency in areas of high sun exposure, such as Arizona, are limited.

Objective: The purpose of this study was to analyze serum 25-hydroxyvitamin D [25(OH)D] concentrations in residents of southern Arizona and to evaluate predictors of 25(OH)D in this population.

Design: Cross-sectional analyses of serum from participants in a colorectal adenoma prevention study were conducted to determine rates of vitamin D deficiency. Participants were categorized into 4 groups on the basis of serum 25(OH)D concentrations: <10.0 ng/mL, > or =10.0 ng/mL and <20.0 ng/mL, > or =20.0 ng/mL and <30.0 ng/mL, and > or =30.0 ng/mL.

Results: The mean serum 25(OH)D concentration for the total population was 26.1 +/- 9.1 ng/mL. Of 637 participants, 22.3% had 25(OH)D concentrations >30 ng/mL, 25.4% had concentrations <20 ng/mL, and 2.0% had concentrations <10 ng/mL. Blacks (55.5%) and Hispanics (37.6%) were more likely to have deficient 25(OH)D concentrations (<20 ng/mL) than were non-Hispanic whites (22.7%). Sun exposure had a greater effect on 25(OH)D in whites than in blacks and Hispanics, whereas BMI appeared to be more important in the latter groups.

Conclusion: Despite residing in a region with high chronic sun exposure, adults in southern Arizona are commonly deficient in vitamin D deficiency, particularly blacks and Hispanics.

Publication types

  • Randomized Controlled Trial
  • Research Support, N.I.H., Extramural

MeSH terms

  • Adult
  • Aged
  • Aged, 80 and over
  • Arizona / epidemiology
  • Black or African American
  • Colorectal Neoplasms / blood
  • Colorectal Neoplasms / epidemiology
  • Cross-Sectional Studies
  • Double-Blind Method
  • Ethnicity*
  • Female
  • Health Status
  • Hispanic or Latino
  • Humans
  • Male
  • Middle Aged
  • Neoplasm Recurrence, Local
  • Nutritional Status*
  • Prevalence
  • Skin Pigmentation / physiology*
  • Sunlight*
  • Vitamin D / analogs & derivatives*
  • Vitamin D / blood
  • Vitamin D Deficiency / epidemiology*
  • White People

Substances

  • Vitamin D
  • 25-hydroxyvitamin D