Abstract
The authors analyze and present the results of spectroscopic studies into changes in the accumulation of the photosensitizer Photosens, its elimination kinetics and distribution in the tissues of the eye and eyelids, as well as in the tumors that have developed at these sites. The findings allowed the authors to estimate the duration of the agent's persistence in the eye tissues and the time interval associated with the high risk for phototoxic eyelid skin and conjunctival reactions and to determine a possibility of and conditions for photodynamic therapy, as well as the length of hospital stay when the latter was performed.
Publication types
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Comparative Study
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English Abstract
MeSH terms
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Conjunctiva / metabolism*
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Conjunctival Neoplasms / diagnosis
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Conjunctival Neoplasms / drug therapy*
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Conjunctival Neoplasms / metabolism
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Diagnosis, Differential
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Eyelid Neoplasms / diagnosis
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Eyelid Neoplasms / drug therapy*
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Eyelid Neoplasms / metabolism
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Eyelids / metabolism*
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Humans
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Indoles / pharmacokinetics*
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Indoles / therapeutic use
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Organometallic Compounds / pharmacokinetics*
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Organometallic Compounds / therapeutic use
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Radiation-Sensitizing Agents / pharmacokinetics*
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Radiation-Sensitizing Agents / therapeutic use
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Spectrometry, Fluorescence
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Treatment Outcome
Substances
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Indoles
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Organometallic Compounds
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Radiation-Sensitizing Agents
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aluminum tetrasulfophthalocyanine