Look who's talking: nuclear receptors in the liver and gastrointestinal tract

Cell Metab. 2008 Mar;7(3):195-9. doi: 10.1016/j.cmet.2008.02.006.

Abstract

The Nuclear Receptors in Liver and Digestive Diseases research workshop was held in Rockville, Maryland, on November 7 and 8, 2007, under the auspices of the National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health. Over 130 researchers from around the world gathered to assess the pathophysiology of nuclear receptors in the liver and gastrointestinal tract and to explore their potential use as therapeutic targets. This review covers some of the highlights of the meeting, including important areas of future investigation.

Publication types

  • Congress
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Bile Acids and Salts / metabolism
  • Cholestasis / drug therapy
  • Cholestasis / metabolism
  • Cholesterol / metabolism
  • DNA-Binding Proteins / metabolism
  • Fasting / metabolism
  • Fatty Liver / drug therapy
  • Fatty Liver / metabolism
  • Fibroblast Growth Factors / metabolism
  • Gastrointestinal Agents / pharmacology
  • Gastrointestinal Agents / therapeutic use
  • Gastrointestinal Tract / drug effects
  • Gastrointestinal Tract / metabolism*
  • Humans
  • Inflammatory Bowel Diseases / drug therapy
  • Inflammatory Bowel Diseases / metabolism
  • Liver / drug effects
  • Liver / metabolism*
  • Nuclear Receptor Subfamily 1, Group D, Member 1
  • Postprandial Period
  • Receptors, Cytoplasmic and Nuclear / drug effects
  • Receptors, Cytoplasmic and Nuclear / metabolism*
  • Signal Transduction* / drug effects

Substances

  • Bile Acids and Salts
  • DNA-Binding Proteins
  • Gastrointestinal Agents
  • NR1D1 protein, human
  • Nuclear Receptor Subfamily 1, Group D, Member 1
  • Receptors, Cytoplasmic and Nuclear
  • Fibroblast Growth Factors
  • Cholesterol