A new cytotoxic xanthone from Garcinia rigida

Berna Elya; Hong Ping He; Soleh Kosela; Muhammad Hanafi; Xiao Jiang Hao

doi:10.1016/j.fitote.2007.11.022

A new cytotoxic xanthone from Garcinia rigida

Fitoterapia. 2008 Apr;79(3):182-4. doi: 10.1016/j.fitote.2007.11.022. Epub 2008 Feb 9.

Authors

Berna Elya¹, Hong Ping He, Soleh Kosela, Muhammad Hanafi, Xiao Jiang Hao

Affiliation

¹ Kunming Institute of Botany, Chinese Academy of Sciences, Kunming 650204, Yunnan, China. elya64@yahoo.com

PMID: 18313861
DOI: 10.1016/j.fitote.2007.11.022

Abstract

A new xanthone, yahyaxanthone (1), was isolated from Garcinia rigida leaves. Cytotoxicity evaluation showed that 1 was inhibitory to L1210 cell, with an IC50 value 4.08 microg/ml.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Animals
Antineoplastic Agents, Phytogenic / administration & dosage
Antineoplastic Agents, Phytogenic / chemistry
Antineoplastic Agents, Phytogenic / pharmacology*
Antineoplastic Agents, Phytogenic / therapeutic use
Cell Line, Tumor / drug effects
Garcinia*
Inhibitory Concentration 50
Magnetic Resonance Spectroscopy
Mice
Phytotherapy*
Plant Extracts / administration & dosage
Plant Extracts / chemistry
Plant Extracts / pharmacology*
Plant Extracts / therapeutic use
Plant Leaves
Xanthones / administration & dosage
Xanthones / chemistry
Xanthones / pharmacology
Xanthones / therapeutic use

Substances

Antineoplastic Agents, Phytogenic
Plant Extracts
Xanthones