Glutathionyl haemoglobin is not increased in diabetes nor related to glycaemia, complications, dyslipidaemia, inflammation or other measures of oxidative stress

Peter Hoffmann; Jade Woon; Kevin G Rowley; Connie Karschimkus; Craig L Nelson; George Dragicevic; David O'Neal; Andrew Wilson; Kevin D Croft; Trevor A Mori; Bruce E Kemp; James D Best; Alicia J Jenkins

doi:10.1016/j.diabres.2008.01.012

Glutathionyl haemoglobin is not increased in diabetes nor related to glycaemia, complications, dyslipidaemia, inflammation or other measures of oxidative stress

Diabetes Res Clin Pract. 2008 May;80(2):e1-3. doi: 10.1016/j.diabres.2008.01.012. Epub 2008 Mar 3.

Authors

Peter Hoffmann¹, Jade Woon, Kevin G Rowley, Connie Karschimkus, Craig L Nelson, George Dragicevic, David O'Neal, Andrew Wilson, Kevin D Croft, Trevor A Mori, Bruce E Kemp, James D Best, Alicia J Jenkins

Affiliation

¹ St. Vincent's Institute of Medical Research, Fitzroy, Melbourne, Australia. Peter.Hoffmann@adelaide.edu.au

PMID: 18313786
DOI: 10.1016/j.diabres.2008.01.012

Abstract

Modified haemoglobin levels were quantified in 21 Type 1 and 21 Type 2 diabetic patients and two groups of 17 non-diabetic subjects. Glycated haemoglobin levels were increased in diabetes but glutathionyl haemoglobin (HbSSG) levels did not differ between groups, nor by complications; nor correlate with haemoglobin glycation or vascular risk factors.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Blood Glucose / metabolism*
Diabetes Complications / blood*
Diabetes Mellitus / blood*
Dyslipidemias / blood*
Glutathione / metabolism*
Hemoglobins / metabolism*
Humans
Inflammation / blood*
Oxidative Stress*

Substances

Blood Glucose
Hemoglobins
glutathionyl hemoglobin
Glutathione