Abstract
In this issue of Molecular Cell, Mariner et al. (2008) demonstrate that Alu RNA from a human SINE represses RNA polymerase II transcription during heat shock. This noncoding RNA is the first example of a "protein-like" transcription factor with a distinct modular architecture.
MeSH terms
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Animals
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Heat-Shock Response / physiology
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Humans
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Nucleic Acid Conformation
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RNA Polymerase II / antagonists & inhibitors
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RNA Polymerase II / genetics
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RNA Polymerase II / metabolism
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RNA, Untranslated* / chemistry
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RNA, Untranslated* / genetics
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RNA, Untranslated* / metabolism
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Short Interspersed Nucleotide Elements / genetics*
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Transcription, Genetic*
Substances
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RNA, Untranslated
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RNA Polymerase II