Towards the genetic treatment of beta-thalassemia: new disease models, new vectors, new cells

Haematologica. 2008 Mar;93(3):325-30. doi: 10.3324/haematol.12732.
No abstract available

Publication types

  • Comment
  • Editorial

MeSH terms

  • Animals
  • Cell Dedifferentiation
  • Disease Models, Animal*
  • Fibroblasts / cytology
  • Gene Deletion
  • Genes, Synthetic
  • Genetic Therapy*
  • Genetic Vectors / therapeutic use*
  • Globins / genetics
  • Humans
  • Lentivirus / genetics
  • Mice
  • Mice, Inbred C57BL
  • Mice, Inbred NOD
  • Mice, Mutant Strains
  • Mice, SCID
  • Mice, Transgenic
  • Recombinant Fusion Proteins / physiology
  • Stem Cell Transplantation* / adverse effects
  • Stem Cell Transplantation* / methods
  • Transgenes
  • beta-Thalassemia / genetics
  • beta-Thalassemia / surgery
  • beta-Thalassemia / therapy*

Substances

  • Recombinant Fusion Proteins
  • Globins