Nitric oxide release mediated by calix[4]hydroquinones

Eranda Wanigasekara; Carmine Gaeta; Placido Neri; Dmitry M Rudkevich

doi:10.1021/ol800156m

Nitric oxide release mediated by calix[4]hydroquinones

Org Lett. 2008 Mar 20;10(6):1263-6. doi: 10.1021/ol800156m. Epub 2008 Feb 28.

Authors

Eranda Wanigasekara¹, Carmine Gaeta, Placido Neri, Dmitry M Rudkevich

Affiliation

¹ Dipartimento di Chimica, Università di Salerno, Via Ponte don Melillo, I-84084 Fisciano (Salerno), Italy.

PMID: 18303905
DOI: 10.1021/ol800156m

Abstract

Calix[4]monohydroquinone has been used as a supramolecular system for the generation of NO gas. In a one-electron reduction scheme involving NO+ subsetcalix[4]monohydroquinone complex, NO is released without the presence of an external reducing agent. Free calix[4]monoquinone, thus obtained, can be reused for a new NO-releasing cycle after NaBH4-reduction to calix[4]monohydroquinone.

Publication types

Research Support, Non-U.S. Gov't
Research Support, U.S. Gov't, Non-P.H.S.

MeSH terms

Calixarenes / chemistry*
Hydroquinones / chemistry*
Magnetic Resonance Spectroscopy
Nitric Oxide / chemistry*
Spectrophotometry, Ultraviolet

Substances

Hydroquinones
calix(4)hydroquinone
Calixarenes
Nitric Oxide