Objective: To study the changes of vitamin nutritional status of residents in a high-risk area of esophageal cancer.
Methods: 8 towns where nutrition survey had been done were selected, 2 villages were randomly selected from each town and 30 families were randomly selected per village. The blood and 4h burden urine samples were collected from subjects. The serum vitamin A, blood total ascorbic acid and glutathione reductase activition coefficient (AC) in red blood cell were determinde by using of trifluoroacetic acid colorimetry, 2, 4-dinitrophenylhydrazine colorimetric method and Sauberlich method respectively. The contents of vitamin B2 , reduction ascorbic acid and total ascorbic acid in 4h burden urine were measured by using of fluorescent pectrophotometry,2,6-Dichloro-N-(4-hydroxyphenyl)-1,4-benzoquinoneimine titrimetric method and 2,4-dinitrophenylhydrazine colorimetric method respectively. The results were analyzed and compared with those of in 1980, 1983 and 1984. The t-test or chi2-test was carried out.
Results: The level of serum retinal in residents living in Ren cun, Dongyao and Hejian is significantly higher than that of in 1982 (P < 0.01). The level of vitamin B2 in 4h burden urine in residents living in Yaocun, Rencun and Heshun are significantly higher than that of in 1982 or 1984 (P < 0.01). The number of ribflavin deficiency of population living in Dongyao, Hejian, Yaocun and Rencun are significantly lower than that of in 1982 or 1983 (P < 0.01) according to the content of 4h burden urine and glutathione reductase activation coefficient (AC) in red blood cell; the number of vitamin C deficiency of population living in Dongyao, Hejian,Yao cun, Ren cun and Heshun are significantly lower than that of in 1982 or 1983 (P < 0.01) according to blood total ascorbic acid and the ascorbic acid content of 4h-burden urine and.
Conclusion: Vitamin nutritional status of residents in a high-risk area of esophageal cancer have been improved.