A new generation of specific Trypanosoma cruzi trans-sialidase inhibitors

Angew Chem Int Ed Engl. 2008;47(14):2700-3. doi: 10.1002/anie.200705435.
No abstract available

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Crystallography, X-Ray
  • Glycoproteins / antagonists & inhibitors*
  • Glycoproteins / chemistry
  • Glycoproteins / metabolism*
  • Kinetics
  • Models, Molecular
  • Molecular Structure
  • Neuraminidase / antagonists & inhibitors*
  • Neuraminidase / chemistry
  • Neuraminidase / metabolism*
  • Protease Inhibitors / chemical synthesis*
  • Protease Inhibitors / chemistry
  • Protease Inhibitors / pharmacology*
  • Sensitivity and Specificity
  • Trypanosoma cruzi / enzymology*

Substances

  • Glycoproteins
  • Protease Inhibitors
  • trans-sialidase
  • Neuraminidase