Glycosidations of 2-deoxy glycosyl dithiophosphates using a tagged iodine(III)-promoter for simple purification

Eike Kunst; Florian Gallier; Gilles Dujardin; Andreas Kirschning

doi:10.1039/b718642h

Glycosidations of 2-deoxy glycosyl dithiophosphates using a tagged iodine(III)-promoter for simple purification

Org Biomol Chem. 2008 Mar 7;6(5):893-8. doi: 10.1039/b718642h. Epub 2008 Jan 24.

Authors

Eike Kunst¹, Florian Gallier, Gilles Dujardin, Andreas Kirschning

Affiliation

¹ Institut für Organische Chemie and Zentrum für Biomolekulare Wirkstoffe (BMWZ), Leibniz Universität Hannover, Schneiderberg 1b, 30167 Hannover, Germany.

PMID: 18292881
DOI: 10.1039/b718642h

Abstract

The preparation of the 4-i-butylsulfonate derivative of the Zefirov reagent (5) and its use in a novel purification strategy for iodine(III)-promoted glycosidations of 2-deoxy diethyldithiophosphate glycosides is described.

MeSH terms

Alkanesulfonic Acids / chemical synthesis
Alkanesulfonic Acids / chemistry
Glycosides / chemical synthesis*
Glycosides / chemistry
Glycosylation
Hydrocarbons, Iodinated / chemistry*
Molecular Structure
Phosphates / chemical synthesis*
Phosphates / chemistry
Stereoisomerism

Substances

Alkanesulfonic Acids
Glycosides
Hydrocarbons, Iodinated
Phosphates
thiophosphoric acid