Acute generalized exanthematic pustulosis. An atypical case due to nadoxolol?

P Bernard; C Bedane; G Catanzano; J Robbe; J M Bonnetblanc

Acute generalized exanthematic pustulosis. An atypical case due to nadoxolol?

Dermatologica. 1991;182(2):115-8.

Authors

P Bernard¹, C Bedane, G Catanzano, J Robbe, J M Bonnetblanc

Affiliation

¹ Department of Dermatology, CHU Dupuytren, Limoges, France.

PMID: 1828772

Abstract

A 74-year-old woman developed a generalized pustular dermatosis with erythema-multiforme-like and vesiculobullous lesions 10 days after beginning a treatment by nadoxolol. Despite the clinical polymorphism of the eruption, histology constantly revealed the presence of subcorneal pustules, even within the epidermis overlying subepidermal bullae. The eruption spontaneously healed after discontinuation of nadoxolol.

Publication types

Case Reports

MeSH terms

Acute Disease
Aged
Anti-Arrhythmia Agents / adverse effects*
Drug Eruptions / etiology*
Drug Eruptions / pathology
Erythema Multiforme / chemically induced
Erythema Multiforme / pathology
Exanthema / chemically induced*
Exanthema / pathology
Female
Humans
Oximes / adverse effects*
Skin / pathology
Skin Diseases, Vesiculobullous / chemically induced
Skin Diseases, Vesiculobullous / pathology

Substances

Anti-Arrhythmia Agents
Oximes
nadoxolol