TNFRSF1A R92Q mutation in association with a multiple sclerosis-like demyelinating syndrome

Neurology. 2008 Mar 25;70(13 Pt 2):1155-6. doi: 10.1212/01.wnl.0000296279.98236.8a. Epub 2008 Feb 20.

Authors

L A Hoffmann¹, P Lohse, F B König, W Feneberg, R Hohlfeld, T Kümpfel

Affiliation

¹ Institute of Clinical Neuroimmunology, Ludwig-Maximilians-University, Munich, Germany.

PMID: 18287568
DOI: 10.1212/01.wnl.0000296279.98236.8a

No abstract available

Publication types

Case Reports

MeSH terms

Adolescent
Amino Acid Substitution
Brain / metabolism
Brain / pathology*
Brain / physiopathology
Chemotaxis, Leukocyte / genetics
Chemotaxis, Leukocyte / immunology
Chromosome Disorders / genetics
Chromosome Disorders / pathology
Chromosome Disorders / physiopathology
DNA Mutational Analysis
Diagnosis, Differential
Female
Genes, Dominant / genetics*
Genetic Markers / genetics
Genetic Markers / immunology
Genetic Predisposition to Disease / genetics*
Genotype
Hereditary Central Nervous System Demyelinating Diseases / genetics*
Hereditary Central Nervous System Demyelinating Diseases / pathology*
Hereditary Central Nervous System Demyelinating Diseases / physiopathology
Humans
Leukocytes / pathology
Magnetic Resonance Imaging
Multiple Sclerosis / diagnosis
Mutation / genetics
Receptors, Tumor Necrosis Factor, Type I / genetics*
Syndrome
Tumor Necrosis Factor-alpha / immunology

Substances

Genetic Markers
Receptors, Tumor Necrosis Factor, Type I
TNFRSF1A protein, human
Tumor Necrosis Factor-alpha