Co-infection with two different strains of Bordetella pertussis in an infant

J Med Microbiol. 2008 Mar;57(Pt 3):388-391. doi: 10.1099/jmm.0.47602-0.

Abstract

We report co-infection with two phenotypically and genotypically distinct strains of Bordetella pertussis in an infant male hospitalized with a 2-week history of cough, paroxysms and vomiting. Colonies from the two B. pertussis phenotypes were isolated and evaluated by PFGE profile analysis, gene sequence typing and PCR-RFLP of a portion of the 23S rRNA gene. These results demonstrated simultaneous infection with two different strains of B. pertussis.

Publication types

  • Case Reports

MeSH terms

  • Anti-Bacterial Agents / pharmacology*
  • Base Sequence
  • Bordetella pertussis / classification*
  • Bordetella pertussis / drug effects*
  • Bordetella pertussis / genetics
  • Bordetella pertussis / isolation & purification
  • Drug Resistance, Bacterial / genetics*
  • Electrophoresis, Gel, Pulsed-Field
  • Erythromycin / pharmacology*
  • Genes, rRNA / genetics
  • Genotype
  • Humans
  • Infant
  • Male
  • Molecular Sequence Data
  • Phenotype
  • Polymerase Chain Reaction
  • Polymorphism, Restriction Fragment Length
  • RNA, Ribosomal, 23S / genetics
  • Sequence Analysis, DNA
  • Whooping Cough / microbiology*

Substances

  • Anti-Bacterial Agents
  • RNA, Ribosomal, 23S
  • Erythromycin