Lanopropic acid, a novel natural 2,3-secolanostane triterpenoid from Schisandra propinqua var. propinqua

Planta Med. 2008 Feb;74(3):292-5. doi: 10.1055/s-2008-1034306. Epub 2008 Feb 11.

Abstract

A triterpenetricarboxylic acid with a novel 2,3-secolanostane-type framework named lanopropic acid ( 1) was isolated from the aerial parts of Schisandra propinqua var. propinqua. The structure of 1 was elucidated as 2,3-secolanost-9(11),24( Z)-diene-2,3,26-trioic acid on the basis of spectroscopic techniques and X-ray diffraction studies. This is the first report of natural occurrence of 2,3-secolanostane type triterpenoid.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Antineoplastic Agents, Phytogenic / isolation & purification*
  • HT29 Cells
  • Humans
  • K562 Cells
  • Schisandra / chemistry*
  • Triterpenes / chemistry*
  • Triterpenes / isolation & purification

Substances

  • Antineoplastic Agents, Phytogenic
  • Triterpenes
  • lanopropic acid