[Subglottic stenosis in Wegener's granulomatosis]

Ann Otolaryngol Chir Cervicofac. 2008 Feb;125(1):35-9. doi: 10.1016/j.aorl.2007.11.002. Epub 2008 Feb 8.
[Article in French]

Abstract

Objective: Describe the management of subglottic stenosis in a patient with Wegener's granulomatosis.

Material and method: Case report.

Results: We report the case of a 26-year-old woman who presented Wegener granulomatosis and subglottic stenosis, with renal, skin, oropharyngeal, nasal, and paranasal locations. Medical treatment had cured all the locations except the subglottic stenosis. An endoscopic dilatation was performed. Two months later, the endoscopic treatment was repeated twice with intralesional corticosteroid injection. One year later, the patient was in complete functional remission.

Conclusion: Respiratory obstruction in Wegener granulomatosis can result from subglottic stenosis. In this case, intralesional corticosteroid injection seemed to be a good adjunct to local treatment with an effective long-term result.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Anti-Inflammatory Agents / therapeutic use
  • Azathioprine / therapeutic use
  • Female
  • Granulomatosis with Polyangiitis / complications*
  • Granulomatosis with Polyangiitis / diagnostic imaging
  • Granulomatosis with Polyangiitis / drug therapy
  • Humans
  • Immunosuppressive Agents / therapeutic use
  • Laryngoscopy / methods
  • Laryngostenosis / etiology*
  • Nasal Obstruction / etiology
  • Prednisone / therapeutic use
  • Radiography

Substances

  • Anti-Inflammatory Agents
  • Immunosuppressive Agents
  • Azathioprine
  • Prednisone