Rapid field immunoassay for detecting antibody to Sin Nombre virus in deer mice

Emerg Infect Dis. 2007 Oct;13(10):1604-7. doi: 10.3201/eid1310.070383.

Abstract

We developed a 1-hour field enzyme immunoassay (EIA) for detecting antibody to Sin Nombre virus in deer mice (Peromyscus maniculatus). The assay specificity and sensitivity were comparable to those of a standard EIA. This test will permit identification of rodents with antibody to this and perhaps other hantaviruses.

Publication types

  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, P.H.S.
  • Validation Study

MeSH terms

  • Animals
  • Antibodies, Viral / blood*
  • Carrier State / immunology
  • Carrier State / veterinary
  • Carrier State / virology
  • Immunoenzyme Techniques / methods*
  • Peromyscus / immunology
  • Peromyscus / virology*
  • Reagent Kits, Diagnostic / veterinary
  • Sensitivity and Specificity
  • Sentinel Surveillance / veterinary*
  • Sin Nombre virus / immunology*

Substances

  • Antibodies, Viral
  • Reagent Kits, Diagnostic