[A comparative research on quality of Vitmin C Yinqiao tablets from different manufacturers]

Zhongguo Zhong Yao Za Zhi. 2007 Nov;32(22):2364-7.
[Article in Chinese]

Abstract

Objective: To study the different manufacturers Vitmin C (Vc) Yinqiao tablets, and the quality of the analysis of the problem, to provide a theoretical basis for the correct evaluation of the quality of medicines and improving the standard drugs.

Method: 11 manufacturers of 18 batches of samples for determination of the weight of the core tablets, powder samples were observed with microscope, determination of Vc, and the establishment of the Vc Yinqiao tablets HPLC method for determination of chlorogenic acid and arctigenin, chlorogenic acid and arctigenin in the samples were measured and compared.

Result: There is a big difference of microscope and various measured results in different manufacturers products.

Conclusion: Because different manufacturers to produce the same, there are big differences in the quality of the products.

Publication types

  • Comparative Study

MeSH terms

  • Arctium / chemistry
  • Ascorbic Acid / chemistry*
  • Chlorogenic Acid / analysis*
  • Chromatography, High Pressure Liquid
  • Drug Combinations
  • Drugs, Chinese Herbal / chemistry*
  • Drugs, Chinese Herbal / isolation & purification
  • Drugs, Chinese Herbal / standards
  • Furans / analysis*
  • Lignans / analysis*
  • Lonicera / chemistry
  • Plants, Medicinal / chemistry
  • Quality Control
  • Tablets

Substances

  • Drug Combinations
  • Drugs, Chinese Herbal
  • Furans
  • Lignans
  • Tablets
  • Chlorogenic Acid
  • Ascorbic Acid
  • arctigenin