In the title compound, C(15)H(16)N(2)O(6).approximately 3H(2)O, the substituted uracil ring is oriented in the anti position relative to the ribose ring, and the phenyl and uracil rings are oriented in a noncoplanar fashion. The furanose ring adopts a conformation close to 3'-endo, in contrast to the furanose conformation seen in the crystal structure of the synthetic precursor 5-bromouridine, which is close to 2'-endo. The molecule is involved in an extensive hydrogen-bonding network with several water molecules, some of which are disordered.