Abstract
A regiospecific, highly chemo-, diastereo-, and enantioselective one-pot catalytic cascade synthesis of cycloheptane derivatives is presented. In this chiral-amine-catalyzed asymmetric process, six new bonds and five new stereocenters were formed with excellent stereocontrol (>25:1 d.r. and 98- >99 ee).
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Catalysis
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Crystallography, X-Ray
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Cyclization
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Cycloheptanes / chemical synthesis*
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Cycloheptanes / chemistry
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Magnetic Resonance Spectroscopy / methods
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Magnetic Resonance Spectroscopy / standards
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Models, Molecular
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Molecular Structure
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Reference Standards
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Stereoisomerism