Brain stem gliomas: patterns of care in Victoria from 1998-2000

J Clin Neurosci. 2008 Mar;15(3):237-40. doi: 10.1016/j.jocn.2007.04.008. Epub 2008 Jan 15.

Abstract

This study describes the management of and outcomes for adult and paediatric patients with newly diagnosed brain stem gliomas during 1998-2000 in Victoria. Adult patients were identified in a retrospective cohort study conducted by surveying doctors involved in managing incident brainstem glioma cases identified from the population-based Victorian Cancer Registry. Paediatric cases were identified from a retrospective analysis of the Victorian Paediatric Brain tumour database for the same period. Ten adult and 14 paediatric patients were considered eligible for this study. Nine (38%) did not have a histologic diagnosis but were diagnosed on the basis of radiological appearance. Complete macroscopic resection was performed in two patients (8%). A variety of tumour types and grades were observed with surgery and radiotherapy the mainstays of therapy. No adult patients and only eight (57%) paediatric patients received chemotherapy. The median survivals for adult patients, paediatric patients with pontine lesions and paediatric patients with non-pontine lesions were: 57, 10 and 60+ months respectively.

Publication types

  • Clinical Trial
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adolescent
  • Adult
  • Aged
  • Brain Stem Neoplasms / epidemiology
  • Brain Stem Neoplasms / pathology
  • Brain Stem Neoplasms / surgery*
  • Cohort Studies
  • Female
  • Glioma / epidemiology
  • Glioma / pathology
  • Glioma / surgery*
  • Humans
  • Magnetic Resonance Imaging
  • Male
  • Middle Aged
  • Neurosurgery / methods*
  • Registries / statistics & numerical data
  • Retrospective Studies
  • Survival Rate
  • Tomography, X-Ray
  • Victoria / epidemiology