AlAr3(THF): highly efficient reagents for cross-couplings with aryl bromides and chlorides catalyzed by the economic palladium complex of PCy3

Chem Commun (Camb). 2007 Oct 7:(37):3847-9. doi: 10.1039/b707703c.

Abstract

Novel and highly efficient cross couplings of aryl bromides and chlorides with AlAr3(THF) (Ar = Ph, 2,4,6-Me3C6H2, 2-naphthyl or 4-Me3SiC6H4) catalyzed by the economic palladium catalyst of PCy3 are reported without the use of a base and under mild reaction conditions at room temperature or temperatures < or = 60 degrees C even for couplings of bulky aryl halides and the Al(2,4,6-Me3C6H2)3(THF) reagent.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Aluminum / chemistry*
  • Benzene Derivatives / chemical synthesis
  • Benzene Derivatives / chemistry
  • Catalysis
  • Hydrocarbons, Brominated / chemistry*
  • Hydrocarbons, Chlorinated / chemistry*
  • Molecular Structure
  • Organometallic Compounds / chemical synthesis
  • Organometallic Compounds / chemistry*
  • Palladium / chemistry*
  • Stereoisomerism

Substances

  • Benzene Derivatives
  • Hydrocarbons, Brominated
  • Hydrocarbons, Chlorinated
  • Organometallic Compounds
  • Palladium
  • Aluminum