Abstract
Specific PCR products are detected with an antibody-free lateral-flow device by sandwiching them between reporter oligonucleotides covalently attached to gold nanoparticles (GNPs) and capture oligonucleotides covalently attached to a nitrocellulose chromatographic strip.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Collodion / chemistry
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Gold / chemistry*
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Metal Nanoparticles / chemistry*
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Nucleic Acids / chemistry*
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Oligonucleotides / chemistry*
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Polymerase Chain Reaction / instrumentation*
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Polymerase Chain Reaction / methods*
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Reagent Strips
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Sensitivity and Specificity
Substances
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Nucleic Acids
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Oligonucleotides
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Reagent Strips
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Gold
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Collodion