Total synthesis of the C-1027 chromophore core: extremely facile enediyne formation through Sml2-mediated 1,2-elimination

Angew Chem Int Ed Engl. 2008;47(9):1777-9. doi: 10.1002/anie.200704842.
No abstract available

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Aminoglycosides / chemical synthesis*
  • Antibiotics, Antineoplastic / chemical synthesis*
  • Drug Delivery Systems
  • Enediynes / chemical synthesis*
  • Molecular Structure
  • Toluene / analogs & derivatives
  • Toluene / chemistry

Substances

  • Aminoglycosides
  • Antibiotics, Antineoplastic
  • Enediynes
  • C 1027
  • Toluene
  • 4-(trifluoromethyl)benzoic acid