One-step bioengineering of magnetic nanoparticles via a surface diazo transfer/azide-alkyne click reaction sequence

Chem Commun (Camb). 2008 Feb 7:(5):621-3. doi: 10.1039/b716113a. Epub 2007 Dec 4.

Abstract

We have developed an efficient conversion of amino iron oxides to carbohydrate and protein derived nanoparticles with highly conserved bioactivity through a combination of diazo transfer and azide-alkyne click technology.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Alkynes / chemistry*
  • Azides / chemistry*
  • Azo Compounds / chemistry*
  • Carbohydrates / chemical synthesis*
  • Carbohydrates / chemistry
  • Ferrosoferric Oxide / chemistry
  • Magnetics
  • Molecular Structure
  • Nanoparticles / chemistry*
  • Particle Size
  • Proteins / chemical synthesis*
  • Proteins / chemistry
  • Surface Properties

Substances

  • Alkynes
  • Azides
  • Azo Compounds
  • Carbohydrates
  • Proteins
  • Ferrosoferric Oxide