Abstract
Under pre-activation glycosylation conditions, the 4,6-di-O-acetyl-N-acetyloxazolidinone protected donor afforded either excellent beta- or alpha-stereoselectivity simply by means of the addition of hindered base TTBP or the absence of base, leading to the controllable stereochemistry of coupling reactions.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Carbohydrate Conformation
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Glucosamine / analogs & derivatives*
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Glucosamine / chemical synthesis*
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Glucosamine / chemistry
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Glycosylation
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Oxazolidinones / chemical synthesis*
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Oxazolidinones / chemistry
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Stereoisomerism
Substances
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4,6-di-O-acetyl-N-acetyloxazolidinone
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Oxazolidinones
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Glucosamine