Complete inversion of enantioselectivity towards acetylated tertiary alcohols by a double mutant of a Bacillus subtilis esterase

Angew Chem Int Ed Engl. 2008;47(8):1508-11. doi: 10.1002/anie.200704606.
No abstract available

MeSH terms

  • Acetates / chemistry
  • Acetylation
  • Alcohols / chemistry*
  • Alcohols / metabolism*
  • Bacillus subtilis / enzymology*
  • Bacillus subtilis / genetics
  • Binding Sites
  • Esterases / chemistry
  • Esterases / genetics*
  • Esterases / metabolism*
  • Kinetics
  • Models, Molecular
  • Molecular Structure
  • Mutation / genetics*
  • Stereoisomerism

Substances

  • Acetates
  • Alcohols
  • Esterases