Severe necrotizing fasciitis in a human immunodeficiency virus-positive patient caused by methicillin-resistant Staphylococcus aureus

Randall J Olsen; Kevin M Burns; Liang Chen; Barry N Kreiswirth; James M Musser

doi:10.1128/JCM.02029-07

Severe necrotizing fasciitis in a human immunodeficiency virus-positive patient caused by methicillin-resistant Staphylococcus aureus

J Clin Microbiol. 2008 Mar;46(3):1144-7. doi: 10.1128/JCM.02029-07. Epub 2008 Jan 16.

Authors

Randall J Olsen¹, Kevin M Burns, Liang Chen, Barry N Kreiswirth, James M Musser

Affiliation

¹ Department of Pathology and Laboratory Medicine, The Methodist Hospital, and Center for Molecular and Translational Human Infectious Diseases Research, The Methodist Hospital Research Institute, Houston, TX 77030, USA.

Abstract

Methicillin-resistant Staphylococcus aureus (MRSA) is a rarely reported cause of necrotizing fasciitis. We report an unusually severe case of MRSA necrotizing fasciitis in a previously undiagnosed AIDS patient. Molecular analysis revealed that the strain had the USA300/spa1 genotype, now an abundant cause of community-acquired MRSA infection.

Publication types

Case Reports
Research Support, Non-U.S. Gov't
Review

MeSH terms

Adult
Anti-Bacterial Agents / pharmacology
Fasciitis, Necrotizing / microbiology*
HIV Seropositivity / complications*
Humans
Male
Methicillin Resistance*
Microbial Sensitivity Tests
Staphylococcal Infections / microbiology*
Staphylococcus aureus / classification
Staphylococcus aureus / drug effects*
Staphylococcus aureus / genetics

Substances

Anti-Bacterial Agents