Case reports: minocycline-induced hyperpigmentation resolves during oral isotretinoin therapy

J Drugs Dermatol. 2007 Dec;6(12):1232-6.

Abstract

Although disfiguring hyperpigmentation is a well-defined complication of minocycline therapy, modalities to reverse the phenomenon are unpredictable. We report a case of minocycline-induced, blue-black pigmentation in a 23-year-old Hispanic man, which resolved after treatment with oral isotretinoin for acne vulgaris.

Publication types

  • Case Reports

MeSH terms

  • Acne Vulgaris / drug therapy
  • Adult
  • Anti-Bacterial Agents / adverse effects*
  • Dermatologic Agents / therapeutic use*
  • Humans
  • Hyperpigmentation / chemically induced
  • Hyperpigmentation / drug therapy*
  • Hyperpigmentation / pathology
  • Isotretinoin / therapeutic use*
  • Male
  • Minocycline / adverse effects*
  • Skin / pathology

Substances

  • Anti-Bacterial Agents
  • Dermatologic Agents
  • Isotretinoin
  • Minocycline