RETRACTED: Evaluation of the safety and efficacy of bremelanotide, a melanocortin receptor agonist, in female subjects with arousal disorder: a double-blind placebo-controlled, fixed dose, randomized study

J Sex Med. 2008 Apr;5(4):887-897. doi: 10.1111/j.1743-6109.2007.00698.x. Epub 2007 Dec 28.

Abstract

This article has been retracted: please see Elsevier Policy on Article Withdrawal (https://www.elsevier.com/about/our-business/policies/article-withdrawal). This article has been retracted at the request of the Editor-in-Chief. Following the retraction of Dr. Safarinejad's work by other journals, The Journal of Sexual Medicine has undertaken an extensive re-review of all papers Dr. Safarinejad published with the journal. Following an intensive re-evaluation and close scrutiny of the manuscripts, our expert reviewers raised multiple concerning questions about the methodology, results, and statistical interpretation as presented in this article. Dr. Safarinejad was contacted to provide his original data and offer explanations to address the concerns expressed by the reviewers. Dr Safarinejad chose not to respond. Consequently, we can no longer verify the results or methods as presented and therefore retract the article.

Publication types

  • Randomized Controlled Trial

MeSH terms

  • Administration, Intranasal
  • Adult
  • Dose-Response Relationship, Drug
  • Double-Blind Method
  • Female
  • Humans
  • Libido / drug effects*
  • Peptides, Cyclic / administration & dosage*
  • Receptor, Melanocortin, Type 3 / agonists*
  • Receptor, Melanocortin, Type 4 / agonists*
  • Sexual Dysfunction, Physiological / drug therapy*
  • Sexual Dysfunctions, Psychological / drug therapy*
  • Statistics, Nonparametric
  • Surveys and Questionnaires
  • Treatment Outcome
  • Women's Health
  • alpha-MSH / administration & dosage*

Substances

  • Peptides, Cyclic
  • Receptor, Melanocortin, Type 3
  • Receptor, Melanocortin, Type 4
  • alpha-MSH
  • bremelanotide