Vasorelaxation and antispasmodic effects of Kaempferia parviflora ethanolic extract in isolated rat organ studies

Fitoterapia. 2008 Apr;79(3):214-6. doi: 10.1016/j.fitote.2007.11.017. Epub 2007 Dec 4.

Abstract

The ethanolic extract of Kaempferia parviflora (KP) rhizomes dose-dependently relaxed both aortic rings and ileum precontracted with phenylephrine and acethylcholine, respectively.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Acetylcholine
  • Animals
  • Aorta / drug effects
  • Aorta / physiopathology
  • Dose-Response Relationship, Drug
  • Humans
  • Ileum / drug effects
  • Ileum / physiopathology
  • Male
  • Muscle Relaxation / drug effects*
  • Muscle, Smooth, Vascular / drug effects*
  • Muscle, Smooth, Vascular / physiopathology
  • Phenylephrine
  • Phytotherapy*
  • Plant Extracts / administration & dosage
  • Plant Extracts / pharmacology*
  • Plant Extracts / therapeutic use
  • Rats
  • Rats, Wistar
  • Rhizome
  • Vasodilator Agents / administration & dosage
  • Vasodilator Agents / pharmacology*
  • Vasodilator Agents / therapeutic use
  • Zingiberaceae*

Substances

  • Plant Extracts
  • Vasodilator Agents
  • Phenylephrine
  • Acetylcholine