Acute poisonings treated in hospitals in Oslo: a one-year prospective study (I): pattern of poisoning

Clin Toxicol (Phila). 2008 Jan;46(1):35-41. doi: 10.1080/15563650601185969.

Abstract

Objectives: Prospective design is mandatory to study pattern of poisoning and suicidal intention of patients.

Material and methods: Prospective cross-sectional multi-center study of all patients contacting health care services because of acute poisoning during one year in Oslo, irrespective of intention. Data on the adult hospitalized patients (> or = 16 years) are presented here.

Results: Of a total of 3,775 such adult contacts (3,025 episodes), there were 947 (31 %) hospitalizations; annual incidence 1.9 (per 1,000) in males and 2.1 in females. Median age was 36 years (range 16-89); 54% females. Benzodiazepines (18%), ethanol (17%), paracetamol (12%), opioids (7%), and gamma hydroxybutyric acid (GHB) (7%) were most frequently taken. Patients stated suicidal intention in 29% of the admissions; physicians in 10%.

Conclusion: Benzodiazepines and ethanol were the most common agents, but newer illicit drugs were frequent, especially GHB. Males often took ethanol and drugs of abuse; females often used prescription drugs with suicidal intention.

Publication types

  • Multicenter Study
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Acetaminophen / poisoning
  • Adolescent
  • Adult
  • Age Factors
  • Aged
  • Aged, 80 and over
  • Analgesics, Opioid / poisoning
  • Benzodiazepines / poisoning
  • Cross-Sectional Studies
  • Ethanol / poisoning
  • Female
  • Hospitalization / statistics & numerical data
  • Humans
  • Hydroxybutyrates / poisoning
  • Incidence
  • Male
  • Middle Aged
  • Norway / epidemiology
  • Poisoning / epidemiology*
  • Prospective Studies
  • Sex Factors
  • Suicide, Attempted / statistics & numerical data*

Substances

  • Analgesics, Opioid
  • Hydroxybutyrates
  • Benzodiazepines
  • 4-hydroxybutyric acid
  • Acetaminophen
  • Ethanol