A live birth after transfer of a day 2 embryo derived from frozen-thawed zygotes that had undergone polar body biopsy: a case report

Fertil Steril. 2008 Oct;90(4):1201.e9-11. doi: 10.1016/j.fertnstert.2007.09.037. Epub 2007 Dec 31.

Abstract

Objective: To present a live birth after freezing and thawing of biopsied oocytes.

Design: Case report.

Setting: Artificial reproduction unit of a university hospital.

Patient(s): A primary infertile couple with asthenoteratozoospermia and repeated failures of intracytoplasmic sperm injection (ICSI).

Intervention(s): Screening of aneuploidy during the fourth ICSI cycle with polar body biopsy (PB) for repeated failures of artificial reproductive techniques and a transfer of a cryopreserved day 2 embryo derived from cryopreserved zygotes with slow-rate freezing after PB.

Main outcomes measure(s): Live birth, viability, and survival.

Result(s): A successful pregnancy and a live birth were presented after a transfer of day 2 embryos derived from oocytes that underwent PB and subsequent cryopreservation.

Conclusion(s): Pregnancy can be obtained subsequent to cryopreservation and thawing after PB.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Cryopreservation*
  • Embryo Transfer / methods*
  • Female
  • Humans
  • Infertility / pathology*
  • Infertility / therapy*
  • Live Birth*
  • Male
  • Treatment Outcome
  • Zygote / cytology*