Comparative study of virulence traits of Escherichia coli clinical isolates causing early and late neonatal sepsis

J Clin Microbiol. 2008 Mar;46(3):1123-5. doi: 10.1128/JCM.01682-07. Epub 2007 Dec 26.

Abstract

Neonatal meningitis and septicemia caused by Escherichia coli are still major health problems in industrialized countries. Forty-seven E. coli strains causing neonatal sepsis were analyzed. Twenty-two and 25 strains caused early (detected from 0 to 3 days after birth) and late (detected from 4 to 28 days after birth) infections, respectively. Only the ibeA gene was significantly more prevalent in the strains causing early infections.

Publication types

  • Comparative Study
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Escherichia coli / genetics
  • Escherichia coli / isolation & purification*
  • Escherichia coli / pathogenicity*
  • Escherichia coli Infections / microbiology*
  • Escherichia coli Proteins / genetics
  • Humans
  • Infant, Low Birth Weight
  • Infant, Newborn
  • Infant, Premature
  • Infant, Premature, Diseases / microbiology*
  • Infant, Very Low Birth Weight
  • Meningitis, Escherichia coli / microbiology
  • Phylogeny
  • Sepsis / microbiology*
  • Time Factors
  • Virulence
  • Virulence Factors / genetics*

Substances

  • Escherichia coli Proteins
  • Virulence Factors