Abstract
We present a new type of azide-functionalized gold nanoparticle and their coupling to an alkyne-modified DNA duplex using the copper(I)-catalyzed Huisgen cycloaddition ('click chemistry'), resulting in a chain-like assembly of nanoparticles on the DNA template.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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DNA / chemistry*
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DNA / ultrastructure
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Gold / chemistry*
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Metal Nanoparticles / chemistry*
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Metal Nanoparticles / ultrastructure
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Microscopy, Atomic Force
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Microscopy, Electron, Transmission
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Molecular Structure
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Templates, Genetic