Effect of chemotherapy on primary mucosa-associated lymphoid tissue lymphoma of the orbit

J Oral Maxillofac Surg. 2008 Jan;66(1):16-20. doi: 10.1016/j.joms.2007.04.018.

Abstract

Purpose: To present a treatment plan for localized mucosa-associated lymphoid tissue lymphoma of the orbit in order to preserve vital structures and function from the side effects of radiotherapy.

Materials and methods: Study of 2 clinical cases by means of clinical and radiologic examination, with 2 and 3 years follow-up, respectively.

Results: Immediate remission of the disease after 6 cycles of chemotherapy, with no signs of recurrence after 2 and 3 years. Clinical examination of the oculomotor mechanism and visual activity gave excellent results.

Conclusion: Although radiotherapy is preferable for localized lymphoproliferative lesions, chemotherapy should also be considered as an effective treatment that preserves the integrity and function of the ocular adnexa.

Publication types

  • Case Reports

MeSH terms

  • Aged
  • Antigens, CD / analysis
  • Biomarkers, Tumor / analysis
  • Drug Therapy, Combination
  • Exophthalmos / etiology
  • Female
  • Humans
  • Lymphoma, B-Cell, Marginal Zone / drug therapy*
  • Lymphoma, B-Cell, Marginal Zone / pathology
  • Lymphoma, B-Cell, Marginal Zone / surgery
  • Male
  • Middle Aged
  • Neoplasm Recurrence, Local / prevention & control
  • Orbital Neoplasms / drug therapy*
  • Tomography, X-Ray Computed
  • Treatment Outcome

Substances

  • Antigens, CD
  • Biomarkers, Tumor