Autophagy and cell death: no longer at odds

Cell. 2007 Dec 14;131(6):1032-4. doi: 10.1016/j.cell.2007.11.027.

Abstract

Autophagy has been associated with both cell survival and cell death, but the role of autophagy in cell death has been controversial. In this issue, Berry and Baehrecke (2007) report that autophagy is involved in physiological cell death during Drosophila development and is controlled by similar mechanisms as those that control its function in cell survival.

Publication types

  • Comment
  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Autophagy*
  • Cell Death*
  • Cell Survival
  • Drosophila