Abstract
Twenty-two non-repetitive carbapenem-resistant Acinetobacter baumannii isolates were obtained from Intensive Care Unit patients. All of the isolates carried bla(OXA-23), bla(OXA-66), a novel cephalosporinase-encoding gene (bla(ADC-25)) and a class 1 integron with an aacC1-orfP-orfQ-aadA1a cassette array and had identical enterobacterial repetitive intergenic consensus (ERIC) profiles. ISAba1 was found upstream of bla(OXA-23), but was not associated with bla(OXA-66) or bla(ADC-25).
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Acinetobacter Infections / epidemiology*
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Acinetobacter Infections / microbiology*
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Acinetobacter baumannii / drug effects*
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Acinetobacter baumannii / isolation & purification
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Carbapenems / pharmacology*
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China / epidemiology
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DNA, Bacterial / chemistry
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DNA, Bacterial / genetics
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Disease Outbreaks*
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Drug Resistance, Bacterial / genetics*
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Humans
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Integrons
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Intensive Care Units
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Interspersed Repetitive Sequences
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Molecular Sequence Data
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Sequence Analysis, DNA
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beta-Lactamases / biosynthesis
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beta-Lactamases / genetics*
Substances
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Carbapenems
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DNA, Bacterial
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beta-Lactamases
Associated data
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GENBANK/EF016355
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GENBANK/EF016356
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GENBANK/EF016357
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GENBANK/EF033072
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GENBANK/EF033073