Weed growth inhibitors from Aspergillus fischeri TISTR 3272

Nat Prod Res. 2007 Dec;21(14):1286-91. doi: 10.1080/14786410701766364.

Abstract

Chloroform and ethyl acetate extracts of Aspergillus fischeri TISTR 3272 showed good growth inhibitory activity on Mimosa pigra and Echinochloa crus-galli. Bioassay-directed fractionation of the active extracts led to the isolation of five known compounds, (+)-terrein (1), (-)-6-hydroxymellein (2), two diketopiperazines (cyclo-(S-Pro-S-Leu) (3) and cyclo-(S-Pro-S-Val) (4)) and butyrolactone I (5). Compounds 2-5 were reported for the first time in this fungus. Their structural determinations were based on analyses of spectroscopic data and their weed growth inhibitory effects were assessed.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • 4-Butyrolactone / analogs & derivatives
  • 4-Butyrolactone / chemistry
  • 4-Butyrolactone / isolation & purification
  • 4-Butyrolactone / pharmacology
  • Aspergillus / chemistry*
  • Cyclopentanes / chemistry
  • Cyclopentanes / isolation & purification
  • Cyclopentanes / pharmacology
  • Diketopiperazines / chemistry
  • Diketopiperazines / isolation & purification
  • Diketopiperazines / pharmacology
  • Echinochloa / drug effects*
  • Echinochloa / growth & development
  • Herbicides / chemistry
  • Herbicides / isolation & purification
  • Herbicides / pharmacology*
  • Isocoumarins / chemistry
  • Isocoumarins / isolation & purification
  • Isocoumarins / pharmacology
  • Mimosa / drug effects*
  • Mimosa / growth & development
  • Molecular Structure
  • Ochratoxins / chemistry
  • Ochratoxins / isolation & purification
  • Ochratoxins / pharmacology
  • Peptides, Cyclic / chemistry
  • Peptides, Cyclic / isolation & purification
  • Peptides, Cyclic / pharmacology

Substances

  • Cyclopentanes
  • Diketopiperazines
  • Herbicides
  • Isocoumarins
  • Ochratoxins
  • Peptides, Cyclic
  • terrein
  • butyrolactone I
  • 4-Butyrolactone
  • ochracin