Abstract
Chloroform and ethyl acetate extracts of Aspergillus fischeri TISTR 3272 showed good growth inhibitory activity on Mimosa pigra and Echinochloa crus-galli. Bioassay-directed fractionation of the active extracts led to the isolation of five known compounds, (+)-terrein (1), (-)-6-hydroxymellein (2), two diketopiperazines (cyclo-(S-Pro-S-Leu) (3) and cyclo-(S-Pro-S-Val) (4)) and butyrolactone I (5). Compounds 2-5 were reported for the first time in this fungus. Their structural determinations were based on analyses of spectroscopic data and their weed growth inhibitory effects were assessed.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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4-Butyrolactone / analogs & derivatives
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4-Butyrolactone / chemistry
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4-Butyrolactone / isolation & purification
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4-Butyrolactone / pharmacology
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Aspergillus / chemistry*
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Cyclopentanes / chemistry
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Cyclopentanes / isolation & purification
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Cyclopentanes / pharmacology
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Diketopiperazines / chemistry
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Diketopiperazines / isolation & purification
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Diketopiperazines / pharmacology
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Echinochloa / drug effects*
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Echinochloa / growth & development
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Herbicides / chemistry
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Herbicides / isolation & purification
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Herbicides / pharmacology*
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Isocoumarins / chemistry
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Isocoumarins / isolation & purification
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Isocoumarins / pharmacology
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Mimosa / drug effects*
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Mimosa / growth & development
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Molecular Structure
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Ochratoxins / chemistry
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Ochratoxins / isolation & purification
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Ochratoxins / pharmacology
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Peptides, Cyclic / chemistry
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Peptides, Cyclic / isolation & purification
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Peptides, Cyclic / pharmacology
Substances
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Cyclopentanes
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Diketopiperazines
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Herbicides
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Isocoumarins
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Ochratoxins
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Peptides, Cyclic
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terrein
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butyrolactone I
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4-Butyrolactone
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ochracin