Synthesis and spectral characterization of 2'-hydroxy chalconate complexes of ruthenium(II) and their catalytic and biological applications

M Muthukumar; P Viswanathamurthi; K Natarajan

doi:10.1016/j.saa.2007.10.043

Synthesis and spectral characterization of 2'-hydroxy chalconate complexes of ruthenium(II) and their catalytic and biological applications

Spectrochim Acta A Mol Biomol Spectrosc. 2008 Oct;70(5):1222-6. doi: 10.1016/j.saa.2007.10.043. Epub 2007 Nov 7.

Authors

M Muthukumar¹, P Viswanathamurthi, K Natarajan

Affiliation

¹ Department of Chemistry, Periyar University, Salem 636011, India.

PMID: 18068426
DOI: 10.1016/j.saa.2007.10.043

Abstract

The reactions of [RuHCl(CO)(B)(EPh3)2] (B=EPh3 or pyridine; E=P or As) and 2'-hydroxychalcones in 1:2 ratio led to the formation of [Ru(CO)(B)(L)2] (B=PPh3, AsPh3 or Py; L=2'-hydroxychalcones). The new complexes have been characterized by analytical and spectral (IR, electronic and 1H NMR) data. They have been assigned an octahedral structure. The new complexes were found to catalyze the oxidation of alcohols to aldehydes using N-methylmorpholine-N-oxide as co-oxidant. All the new complexes were found to be active against bacteria such as E. coli, Salmonella typhi and fungi Aspergillus niger. The activity was compared with standard Streptomycin or Bavistin.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Anti-Bacterial Agents / chemistry*
Anti-Bacterial Agents / pharmacology*
Antifungal Agents / chemistry*
Antifungal Agents / pharmacology*
Catalysis
Chalcone / analogs & derivatives*
Electrons
Microbial Viability / drug effects
Molecular Structure
Ruthenium Compounds / chemistry*
Ruthenium Compounds / pharmacology*
Spectrum Analysis

Substances

Anti-Bacterial Agents
Antifungal Agents
Ruthenium Compounds
Chalcone