Objective: To report the experience in the diagnosis and treatment of focal nodular hyperplasia (FNH) of liver.
Methods: The clinical data of 23 patients with FND in liver, 15 males and 8 females, aged 38 (22 - 53), were analyzed retrospectively.
Results: Thirteen of the 23 patients had been diagnosed as with FNH of liver before operation. The diagnosis of 12 cases was confirmed by CT or MRI. One case underwent ultrasonography guided biopsy. The diameters of tumor ranged 0.8 - 8 cm. All the 23 patients underwent resection of tumor with an uneventful recovery and without recurrence during the follow-up period. Altogether 27 tumor nodes had been resected. The diagnosis was confirmed by histological examination in all of the patients.
Conclusion: CT and MRI are valuable for the diagnosis of FH of liver. Biopsy guided by ultrasonography leads to histological diagnosis. However, definite preoperative diagnosis remains difficult to make. Surgical resection is necessary when the patient becomes symptomatic or when malignancy cannot be excluded.