Synthesis of 9-(2,3-dideoxy-2,3-difluoro-beta-D-arabinofuranosyl)adenine

Grigorii G Sivets; Elena N Kalinichenko; Igor A Mikhailopulo

doi:10.1080/15257770701534063

Synthesis of 9-(2,3-dideoxy-2,3-difluoro-beta-D-arabinofuranosyl)adenine

Nucleosides Nucleotides Nucleic Acids. 2007;26(10-12):1387-9. doi: 10.1080/15257770701534063.

Authors

Grigorii G Sivets¹, Elena N Kalinichenko, Igor A Mikhailopulo

Affiliation

¹ Institute of Bioorganic Chemistry, National Academy of Sciences, Acad. Kuprevicha 5/2, 220141 Minsk, Belarus. gsivets@yahoo.com

PMID: 18066788
DOI: 10.1080/15257770701534063

Abstract

Convergent synthesis of 9-(2,3-dideoxy-2,3-difluoro-beta-D-arabinofuranosyl)adenine is described starting from methyl 5-O-benzyl-2-deoxy-2-fluoro-alpha-D-arabinofuranoside.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Adenine / chemistry*
Dideoxyadenosine / analogs & derivatives*
Dideoxyadenosine / chemical synthesis

Substances

9-(2,3-dideoxy-2,3-difluoro-beta-D-arabinofuranosyl)adenine
Dideoxyadenosine
Adenine