Synthesis of new L-ascorbic ferulic acid hybrids

Molecules. 2007 Nov 17;12(11):2533-45. doi: 10.3390/12112533.

Abstract

A feasibility and chemical study of the coupling conditions of L-ascorbic acid with ferulic acid derivatives are described on the basis of the known synergistic effects of mixtures of various antioxidants. Novel L-ascorbic ferulic hybrids linked at the C-3 hydroxyl group were prepared with the aim to protect the alcohol function and the enediol system.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Antioxidants* / chemical synthesis
  • Antioxidants* / chemistry
  • Ascorbic Acid* / chemical synthesis
  • Ascorbic Acid* / chemistry
  • Coumaric Acids* / chemical synthesis
  • Coumaric Acids* / chemistry
  • Humans
  • Molecular Structure
  • Oxidants / chemistry
  • Oxidative Stress

Substances

  • Antioxidants
  • Coumaric Acids
  • Oxidants
  • ferulic acid
  • Ascorbic Acid